Estrone

IUPAC Name: (8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one

Source: Occurs naturally in urine of pregnant women and mares. Used as a hormone therapy treatment medicine, and for menopausal treatment. It is also used to prevent osteoporosis. It may be used for its antineoplastic properties.

 Summary: Estrone is a naturally occurring estrogen and steroid found in urine from pregnant women and mares. It is one of the major endogenous estrogens along with estradiol and estriol. It may be synthetically produced for hormone treatment therapy, osteoporosis prevention, or for its antineoplastic properties. It is soluble in water up to 30 mg/L and has a density of 1.236 g/mL at 25 C. Koc values ranging from 457 Р18,000 indicate estrone will not be mobile within soil. Photolysis is expected to be a major fate process within water.

GHS Hazard Statement: H302, H312, H332, H350, H351, H360, H361, H362, H372, H401, H410, H412, GHS07, GHS08, GHS09