Acetamide

IUPAC Name: Ethanamide

Source: Used as a solvent and plasticizer, and as an intermediate in organic synthesis.

Summary: Acetamide is an organic compound that is acetic acid with an amide group. It is formed during the condensation reaction of acetic acid and ammonia. It is commercially produced for uses as a solvent and plasticizer, and is an important intermediate in organic synthesis. It is soluble in water up to 705,000 mg/L at 24.5 C and has a density of 1.159 g/mL at 20 C. Acetamide has a base dissociation constant of pKb = 14.51 at 25 C. The compound is classified by the EPA as a Hazardous Air Pollutant (HAPs). It exists in the atmosphere as a vapor with a half-life of 7.6 days. A Koc value of 5 indicates very high mobility within soil. Biodegradation is expected to be a major method of natural removal in water and soil.

GHS Hazard Statement: H316, H320, H351, H361, GHS08